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Post-Traumatic Knee Osteoarthritis Following Anterior Cruciate Ligament Reconstruction

Exploring knee osteoarthritis after ACL surgery in a clinical trial.

Recruiting
18-35 years
All
Phase N/A

This study looks at how the knee joint works after an Anterior Cruciate Ligament (ACL) Reconstruction, which is a surgery to fix a torn ACL, a key ligament for knee stability. The research will take place over two years and will explore how the knee joint mechanics (how the knee moves and bears weight) affect the cartilage, the smooth tissue covering the ends of bones. This is important to understand because changes might lead to Post-Traumatic Knee Osteoarthritis (PTOA), a type of arthritis that can happen after an injury.

Participants will be monitored during activities like walking and climbing stairs to see how their knees handle different pressures. This study involves two key parts: the first part focuses on measuring changes in knee forces; the second looks at how these changes affect cartilage over time.

  • Participation involves regular physical activity and being between 18-35 years old.
  • Volunteers must not have had major recent leg injuries or existing joint diseases.
  • Informed consent is required, meaning participants agree to join the study fully understanding what it involves.
Study details
    Anterior Cruciate Ligament Injuries
    Post-Traumatic Osteoarthritis of Knee

NCT06201442

Universitaire Ziekenhuizen KU Leuven

24 January 2024

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A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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