Multicenter, Open, Prospective, 48 Weeks, Observational Study ,Evaluate the Safety and Efficacy of Nephoxil Capsule

Study Overview: This study is looking at how safe and effective the Nephoxil capsule is in helping CKD (Chronic Kidney Disease) patients on hemodialysis with hyperphosphatemia, which means having too much phosphate in the blood.

Study Details: For 48 weeks, doctors will observe CKD patients on hemodialysis who are taking Nephoxil capsules during their usual medical appointments. No extra visits are needed. The medicine dose will be decided by the doctor and can be adjusted slightly. Patients will be in either a low-dose group (1.5 g/day) or a standard-dose group (4 g/day). The highest dose allowed is 6 g/day.

• **Duration:** 48 weeks with no extra visits needed.
• **Participation:** Must be 19 or older, starting Nephoxil for the first time.
• **Risks:** Cannot take if you need certain other medications or have specific conditions.

**Remember:** Participation is voluntary, and you should discuss with your doctor if this study is right for you.