This study looks at how certain chemicals in the blood (markers) change when someone with acute myeloid leukemia (AML) gets a bone marrow transplant and develops a condition called graft-versus-host disease (GVHD). **GVHD** happens when the new cells attack the body they were put into. The study will measure levels of specific markers, like **Gasdermin-D** and **NLRP-3** (involved in a type of cell death called pyroptosis) to see if they can predict or show how bad GVHD is. Researchers will also check markers of blood vessel damage. The study uses blood samples and images of tiny blood vessels in the nail bed to gather information.

• Participants must have AML and be at least 18 years old.
• The study will follow participants for up to two years.
• If someone leaves the study, new participants will be added.