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Relationship Between Dyslipidemia and The Response of Diabetic Macular Edema to Intravitreal Injection of Anti Vascular Endothelial Growth Factor Agents

Exploring how cholesterol levels affect diabetic eye treatment response.

Recruiting
35-65 years
All
Phase N/A

Diabetic retinopathy (DR) is an eye problem that often causes blindness in adults. It can lead to diabetic macular edema (DME), which makes vision blurry. DME is caused by swelling in the eye, and stopping this swelling can help improve sight. One treatment is anti-VEGF therapy. VEGF stands for *Vascular Endothelial Growth Factor*, a protein that helps grow new blood vessels. Anti-VEGF medicines stop these new blood vessels from forming and leaking, which protects the eye. **Ranibizumab** and **aflibercept** are common anti-VEGF medicines.

Dyslipidemia means having too much *bad cholesterol* and fats in the blood, and it can make eye problems worse. This study is looking at how dyslipidemia affects the success of anti-VEGF treatment for DME. Patients with type II diabetes and DME can participate, but not if they've had certain eye surgeries or treatments.

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Study details
    Diabetic Macular Edema

NCT06205979

Sohag University

24 January 2024

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