Epigenetic Regulation of Colorectal Polyps and Cancer
Epigenetic Regulation of Colorectal Polyps and Cancer is a study aiming to understand how genetic material changes without altering DNA, through microRNA and mRNA, impact colorectal polyps and cancer. MicroRNA and mRNA are small molecules that help control which genes are active in our cells. This study will find out if these molecules are present in different amounts in polyps and cancer at various stages and if they can be detected in blood samples. It will also explore if the bacteria in the intestines, called microbiota, is connected to these conditions. Participants will include patients undergoing colonoscopy where polyps or cancer are found and healthy people with normal results. The study will last 24-48 months, gathering blood and tissue samples from 400 participants. No risks are expected, as these are routine procedures. The study could help create blood tests for early detection of colorectal cancer and improve treatment options.
- Duration: 24-48 months with 400 participants.
- Involves routine blood and tissue sample collection.
- Potential to advance colorectal cancer detection and treatment.
Study details
NCT06206603
Region Skane
24 January 2024
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