The Gut Microbiome and Serum Metabolites as a Biological Mechanism Underlying Pain in Kidney Transplantation

The Gut Microbiome and Serum Metabolites Study aims to understand why people with a new kidney often feel pain. This pain can cause tiredness, sadness, and stop people from enjoying life. The study will look at tiny living things in the body, called the microbiome, and chemicals in the blood, called serum metabolites. These might play a role in the pain experienced after getting a new kidney. Scientists think that diet and stress change these tiny things, which might increase pain. By looking at these changes before and after getting a kidney, researchers hope to find ways to help reduce pain for people with kidney problems. This study is conducted at the University of Illinois in Chicago. Participants must be at least 18 years old and getting a kidney transplant there. People who have certain medical conditions or treatments are not eligible to join.

• Study involves tracking pain, diet, and stress before and after a kidney transplant.
• Must be getting a kidney transplant at University of Illinois Chicago.
• Not eligible if on certain medications or have specific health issues.