Reduction of Gastrointestinal Toxicity in Prostate Cancer by Proton Spot Placement

Study Purpose: This study explores whether a new proton therapy method, called *Spot Delete*, can reduce side effects in men with prostate cancer. Proton therapy uses a beam of charged particles to target cancer. In this study, researchers will test if carefully placing these protons can lower side effects like diarrhea or bladder issues.

• **Duration and Visits:** Patients will participate for the duration of their treatment, with regular visits for monitoring.
• **Risks:** The study has similar risks to regular proton therapy, but aims to reduce bowel and bladder side effects.
• **Eligibility:** Men with low to intermediate prostate cancer, who meet certain health criteria, may join.

Study Method: Participants are divided into two groups. One group uses *Spot Delete* to avoid placing protons near the bowel, which should reduce side effects. The other group gets standard treatment. Researchers will track any side effects and compare results.

Participating in this study may help improve treatment for prostate cancer by reducing uncomfortable side effects. Always discuss with a doctor if joining a study is the right choice for you. 😊