This study is looking at how different treatments can help people with colorectal cancer that has spread to the liver (CRLM). Patients with 10 or more liver metastases will either get local treatments like surgery, ablation (destroying cancer cells), or SBRT (a type of precise radiation), or they will get palliative chemotherapy, which focuses on making patients feel better rather than curing the cancer. Researchers want to see if these local treatments help people live longer than just using palliative chemotherapy.
- Patients will be part of the study after chemotherapy has controlled their cancer.
- Local treatments may include surgery, ablation, or SBRT.
- Participants will be followed for their survival outcomes.
To join, patients need to be at least 18 years old, have controlled disease after chemotherapy, and be able to undergo surgery and/or other local treatments. People with certain health issues or other types of cancer cannot participate. The study aims to find out if localized treatments can help improve survival rates compared to chemotherapy alone for patients with 10 or more liver metastases from colorectal cancer.