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Cardiac Amyloidosis in HFpEF Tunisian Patients

Study on heart condition in Tunisian patients with preserved ejection fraction.

Recruiting
60-90 years
All
Phase N/A

Cardiac Amyloidosis (CA) is a condition where abnormal proteins build up in the heart, causing heart failure with a preserved left ventricular ejection fraction, also known as HFpEF. In simpler terms, the heart struggles to pump blood effectively despite the heart muscle appearing normal. This study focuses on Tunisian patients with HFpEF to see how common CA is and find ways to predict it using clinical checks and ultrasound. Diagnosing CA early can help improve patient outcomes. There are two main types of CA: TTR and AL, and identifying them early is crucial. To participate in this study, patients must have had HFpEF in the past year and a heart wall thickness (IVS) of 12mm or more. The study excludes those under 60, patients with recent heart attacks leading to HFpEF, or congenital (from birth) heart issues.

  • Participants must be 60 years or older.
  • Study focuses on heart ultrasound and clinical assessments.
  • No congenital heart disease or recent heart attack patients allowed.
Study details
    Cardiac Amyloidosis
    Heart Failure With Preserved Ejection Fraction
    Echocardiography
    CMR
    Bone Scintigraphy
    Prevalence
    Diagnosis

NCT06201832

University Tunis El Manar

24 January 2024

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