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Phase II Study of Concurrent Radiotherapy With Envafolimab and Capecitabine in LAPC

Exploring new treatment options for locally advanced pancreatic cancer.

Recruiting
18-90 years
All
Phase 2

This study is testing a new treatment for people with advanced pancreatic cancer that cannot be removed by surgery. The treatment combines a type of radiation called intensity-modulated radiotherapy (IMRT) or volumetric modulated arc therapy (VMAT) with two drugs: envafolimab (an injection) and capecitabine (a pill). These drugs help the radiation work better. To join, patients need to be 18-90 years old, have this specific type of cancer, and meet other health criteria. The study is only for those who haven't had certain treatments before. Participants will receive weekly injections of envafolimab and take capecitabine pills for two weeks followed by one week off. This cycle repeats until the treatment stops working or the patient can't tolerate it.

  • This study requires regular hospital visits for treatment and monitoring.
  • Participants need to be willing to follow the treatment plan and attend follow-ups.
  • Participants should not have any active infections or other serious health conditions.
Study details
    Pancreatic Cancer
    Radiotherapy
    Envafolimab
    Capecitabine

NCT06202014

Cancer Institute and Hospital, Chinese Academy of Medical Sciences

24 January 2024

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What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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