Monitoring Changes in Hepatic Steatosis Using Continuous Controlled Attenuation Parameter

Non-alcoholic fatty liver disease (NAFLD) is when extra fat builds up in the liver not related to alcohol. It can lead to liver problems like cancer and cirrhosis. This study aims to find a better way to monitor liver fat using a new test called the Continuous Controlled Attenuation Parameter (CAPc), compared to the more expensive MRI-PDFF, which is the current gold standard. The study will last 6 months and will involve 150 patients with NAFLD. They will join a lifestyle program to help reduce liver fat through diet and exercise. Participants will visit the clinic four times during the study to check their progress and health. They will have various tests, including blood tests, liver scans, and physical exams. The study hopes to show that CAPc is a good, cheaper, and easier alternative to MRI-PDFF for monitoring liver fat changes.

• Study lasts 6 months with 4 clinic visits.
• Involves lifestyle changes like diet and exercise.
• Tests include blood tests, liver scans, and physical exams.