SBRT Versus Hypofractionated Radiotherapy for Biochemically Recurrent or Oligometastatic Prostate Adenocarcinoma

This study is comparing two types of radiation therapy for prostate adenocarcinoma, a cancer that starts in the prostate gland. The study looks at patients whose cancer has returned or spread to a few new places. The two treatments are SBRT (Stereotactic Body Radiation Therapy), which gives small doses of radiation over a shorter time, and hypofractionated radiation therapy, which gives higher doses but over a longer time. The goal is to see if SBRT is just as good or better than the other treatment by seeing how many side effects they cause and how well they work.

• Participants will be in the study for up to 5 years with follow-ups.
• SBRT involves 5 treatments over 1-2 weeks, while the other therapy involves 20 treatments over 4-6 weeks.
• There is a chance to receive extra treatment called androgen deprivation therapy (ADT) for up to 18 months.

Participants should be 18 or older and have had prostate surgery. Some medical conditions might prevent participation. 🏥📅