F01 in the Treatment of Autoimmune Diseases This study aims to test a new medication called F01 to see if it's safe for people with autoimmune diseases. Autoimmune diseases are conditions where the body's defense system attacks its own cells by mistake. Examples include systemic lupus erythematosus (SLE), vasculitis, and systemic sclerosis. The study involves two main parts: dose escalation, which means gradually increasing the amount of the drug given to participants, and dose extension, which involves giving a set dose over a longer period. Participants must be between 18 to 65 years old and have certain autoimmune diseases that haven't improved with standard treatments. They also need to meet specific health requirements, like having good heart and kidney health. People with severe heart, lung, or other health problems cannot join. Women who can have children and men must agree to use birth control during and after the study. Key Points:

• The study will have up to 20 participants.
• Participants' health will be monitored closely for safety.
• It's important for participants to follow birth control guidelines.