The Relations Among Endotoxin, Inflammatory Cytokines, Cognitive Markers and Brain MRI Changes in Subjects With Depressive Disorder

Major Depressive Disorder (MDD) is a long-term mental illness. It often comes back even after treatment. This study will look at how things like endotoxin (a harmful substance from bacteria) might affect the brain and cause depression. 🧠 Scientists think the immune system and inflammation might play a big role in depression. They want to see if a substance called LPS (lipopolysaccharide) can cause brain inflammation and depression symptoms. They will also look at different genes to see if they change how LPS affects people.

• 🕒 The study requires adult participation (18+ years) with MDD.
• 🔬 Participants need to have blood tests and possibly brain scans.
• 🤝 Participants must sign a consent form and not have other mental disorders.

This study is important because it might help us understand why some people don't get better with normal depression treatments. Understanding this could lead to better ways to help people with depression in the future. 😊