Safety and Efficacy of SHPL-49 Injection in Participants With Acute Ischemic Stroke

This study is testing a new medicine called **SHPL-49** for treating people who have had a stroke. A stroke happens when blood flow to a part of the brain is blocked. This study will see if SHPL-49 is safe and if it helps people recover from a stroke. Participants will receive the medicine through a needle in their arm for 7 days. Some people will get a fake treatment, called a placebo, to compare results. The study includes adults aged 18 to 80 who had a stroke within the last 8 hours.

**Key Points:**

• **Length of the Study:** 7 consecutive days of treatment.
• **Visit Frequency:** Twice a day dosing for the first week.
• **Participation Requirements:** Must have had a stroke recently and meet health criteria.

People who have certain health issues, like brain bleeding or severe heart problems, or those who are pregnant, can't join. Participants will be randomly assigned to receive either the actual medicine or a placebo. This study will help doctors understand if SHPL-49 can be a new treatment for stroke recovery.