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Phase II Study on Neoadjuvant Therapy of AK104 Combined With Nab-paclitaxel/Carboplatin in Fertility Preserving Surgery

Research on AK104 with chemo before fertility-preserving surgery.

Recruiting
18-45 years
Female
Phase 2
**Study Summary:** This research looks at using a combination of drugs, *AK104*, *nab-paclitaxel*, and *carboplatin*, to help treat cervical cancer before surgery. This type of treatment is known as **neoadjuvant therapy**, which means it's used to shrink the tumor before the main treatment, like surgery. The study is for women who want to keep their fertility (ability to have children) even after cancer treatment. The main goals are to see how safe the treatment is and how well it works at reducing the tumor. **Key Points for Participants:** - The study involves taking the medication and attending scheduled visits and tests. - Participants need to be between 18 and 45 years old, with no serious health problems. - Subjects must agree to provide blood and tissue samples for research and meet certain health criteria. Participants must have not received any prior treatment for their cervical cancer and should be willing to follow all study requirements and safety guidelines.
Study details
    Neoadjuvant Immunotherapy
    Cervical Cancer
    Fertility-sparing Surgery

NCT06209294

Xiaohua Wu

24 January 2024

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