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Phase II Study on Neoadjuvant Therapy of AK104 Combined With Nab-paclitaxel/Carboplatin in Fertility Preserving Surgery

Recruiting
18-45 years
Female
Phase 2

This study tests neoadjuvant therapy, which is treatment given before the main treatment, using a drug called AK104 combined with other medicines (nab-paclitaxel and carboplatin) for early-stage cervical cancer. Cervical cancer is a disease where cells in the cervix, the lower part of the uterus, grow uncontrollably. This study focuses on women who want to keep their ability to have children. The main goals are to see if the treatment is safe and how well it works.

Eligibility: Women aged 18-45 with specific types of early-stage cervical cancer, no previous cancer treatment, and good health are needed. They should be willing to give tissue and blood samples for research.

  • đź•’ The study could involve several visits and tests.
  • đź’Š Participants may experience side effects from the drugs.
  • đź’° There may be compensation for time and travel.
Study details
    Neoadjuvant Immunotherapy
    Cervical Cancer
    Fertility-sparing Surgery

NCT06209294

Xiaohua Wu

24 January 2024

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