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PD-1 Antibody Plus Bevacizumab and CAPOX as First-line Treatment for RAS-mut MSS mCRC

Testing new treatment for certain colorectal cancer patients.

Recruiting
18-75 years
All
Phase 2

This study is testing a new combination of treatments for a type of colon cancer called RAS-mutant, microsatellite stable, metastatic colorectal cancer (mCRC). The treatment mix includes an anti-PD-1 antibody (a type of protein that helps the immune system fight cancer), bevacizumab (a drug that stops blood vessels from growing to the tumor), and chemotherapy. This is the first time these drugs will be used together as the initial treatment for this cancer type. Only people who have not had any treatment for their metastatic cancer can join.

Key Points:

  • The study will check how safe and effective the treatment is.
  • Participants must not have other untreated cancers or certain health conditions.
  • Women of childbearing age must use birth control during the study.
Study details
    Colorectal Cancer
    RAS Mutation
    Colorectal Neoplasms
    Microsatellite Stable Colorectal Carcinoma

NCT06206096

Chinese PLA General Hospital

24 January 2024

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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