Use of Allocetra-OTS in End Stage Knee Osteoarthritis - Assessment of Safety

Allocetra-OTS is being tested for safety and how well it might work for people with end-stage knee osteoarthritis (a condition where the knee joint wears down and causes pain and difficulty moving). This study is a "pilot study," which means it's the first step to see if the treatment is safe for people.

To join, you must be at least 18, have a doctor say your knee has end-stage osteoarthritis, and be planning or offered knee surgery. You need a recent X-ray showing osteoarthritis and have blood tests showing your health is good enough. You must understand and agree to the study rules.

If you have a knee infection, already had knee replacement surgery, or have other serious health issues, you cannot join. You also can't join if you're in another study or if you’re pregnant.

• This study checks if the treatment is safe and possibly helpful.
• You need a doctor's okay and must sign a consent form.
• You can't join if you have certain health issues or are pregnant.

Think about joining if you're ready to try a new treatment and can follow the study instructions.