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Neoadjuvant Therapy of HAIC?GEMOX? Combined With Adebrelimab and Lenvatinib for Resectable Intrahepatic Cholangiocarcinoma With High-risk Recurrence Factors?NEO-ERA-01 Study

Exploring new treatment for liver cancer before surgery.

Recruiting
18-75 years
All
Phase 2

This clinical trial aims to test new treatments for a type of liver cancer called **intrahepatic cholangiocarcinoma**, which often comes back after surgery. The study combines several advanced treatments: **HAIC** (Hepatic Arterial Infusion Chemotherapy), **GEMOX** (a combination of drugs gemcitabine and oxaliplatin), **Adebrelimab** (a type of medicine that helps the immune system fight cancer), and **Lenvatinib** (a medicine that stops cancer growth). These are used before surgery to see if they can reduce the cancer, making it easier to remove.

  • The study involves 2-4 cycles of treatment before surgery.
  • Participants must be aged between 18-75 and meet certain health criteria.
  • Participants should expect to follow specific guidelines regarding contraception during the study.

Doctors will measure how well the cancer shrinks with these treatments, and whether the combination is safe for patients. If you're considering joining this study, it's important to discuss any concerns with your doctor, especially regarding the required treatment cycles and potential side effects. 🏥💉

Study details
    Biliary Tract Carcinoma

NCT06208462

The First Affiliated Hospital with Nanjing Medical University

24 January 2024

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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