Predicting Tumor Metastasis by Employing a Target Organ/Primary Lesion Fusion Radiomics Model

Tumor metastasis is when cancer cells spread to other parts of the body. This study uses a special method called radiomics to predict where cancer might spread. *Radiomics* is a new way to study images from medical tests to learn about diseases without needing surgery or invasive procedures. This study looks at three types of cancer: lung, colorectal, and breast cancer, to see if they spread to the brain, liver, or lungs. The study uses the *"seed and soil"* theory, which means cancer cells (seeds) need a good environment (soil) to spread. The goal is to use radiomics to find out if a certain cancer is likely to spread, which can help doctors decide on better treatments.

• This is an observational study, meaning no treatment is given, just observation of data.
• Participants need regular follow-ups and imaging tests.
• Eligible participants will have imaging tests before any cancer spread.