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3D-MRE and 2D-MRE for Assessing Cirrhosis and Portal Hypertension

We're studying 3D-MRE and 2D-MRE to assess liver health.

Recruiting
18-75 years
All
Phase N/A

This study aims to find a new way to predict **portal hypertension** in people with **cirrhosis**. Cirrhosis is when the liver gets badly scarred, and portal hypertension means high blood pressure in the liver's veins. The usual test for this, called Hepatic Venous Pressure Gradient (HVPG), is invasive, meaning it involves entering the body, which can be uncomfortable or risky.

Researchers want to see if a type of scan called **Magnetic Resonance Elastography (MRE)** can predict this pressure without needing to go inside the body. They are comparing two types of MRE: 3D (three-dimensional) and 2D (two-dimensional). These scans use magnets to create pictures of the liver and measure its stiffness, which could help doctors understand liver problems better.

  • **Study Length**: Participants will need MRE scans within a month of the HVPG test.
  • **Who Can Join**: Adults with confirmed cirrhosis who haven't had certain liver conditions or surgeries.
  • **Risks and Benefits**: The study hopes to find a less invasive test with fewer risks than current methods.
Study details
    Cirrhosis
    Liver Portal Hypertension

NCT06205992

Shengjing Hospital

24 January 2024

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