Stereotactic Re-irradiation of Local Recurrences of Prostate Cancer After Radiotherapy

This clinical study is about treating prostate cancer that has returned with a special type of radiation therapy called **Stereotactic Body Radiotherapy (SBRT)**. This treatment uses precise radiation to target cancer cells. The study checks how safe and effective SBRT is in people who have had prostate cancer come back after initial radiation or surgery. Doctors want to know if people can handle this treatment well and if it helps control cancer.

Participants will be divided into three groups based on their previous treatments. The study aims to include **60 patients** over **6 years**. The study will check if SBRT works well and is safe by looking at things like survival and quality of life (how good people feel during treatment).

• **Study Duration:** Up to 6 years with 10 patients per year.
• **Visits Required:** Regular checks with imaging tests like PET and MR.
• **Benefits/Risks:** May improve cancer control; potential side effects include urinary and bowel issues.

To participate, patients need to have prostate cancer that returned after initial treatment but should not have widespread cancer or a history of severe side effects from previous treatments.