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Stereotactic Re-irradiation of Local Recurrences of Prostate Cancer After Radiotherapy

Studying new treatment for returning prostate cancer after radiation.

Recruiting
18-80 years
Male
Phase 2
**Study Summary:** This study is testing a special treatment called *stereotactic body radiotherapy* (SBRT) for men who have prostate cancer that has come back after they've already had radiation therapy. SBRT focuses high doses of radiation directly on the cancer cells, hoping to reduce side effects and be more effective. The main goal is to see how well patients handle this treatment and if it helps control the cancer. **Key Points:** - **Duration & Visits:** The study will last up to 6 years, with 10 patients joining each year, totaling 60 participants. - **Treatment Details:** Patients will receive SBRT, which targets only the visible tumor and uses advanced imaging for accuracy. This treatment doesn't usually require hormone therapy. - **Safety & Efficacy:** The study will monitor if SBRT helps and how well patients tolerate it, using quality of life questionnaires. Patients must have had prostate cancer return after radiation and be in good health. They cannot have widespread cancer or certain health issues that could interfere with SBRT. This study is an important step to see if SBRT can be a safe and effective option for these patients.
Study details
    Local Recurrence of Malignant Tumor of Prostate
    Radiotherapy

NCT06201078

Maria Sklodowska-Curie National Research Institute of Oncology

24 January 2024

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