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Pharmacokinetics of Fixed-Dose Combination Tablet of Bemnifosbuvir and Ruzasvir

Studying how a Bemnifosbuvir and Ruzasvir tablet works in the body.

Recruiting
18-65 years
All
Phase 1
**Study Purpose:** This study examines how the body absorbs a combined tablet of two drugs, Bemnifosbuvir (BEM) and Ruzasvir (RZR), and how food might affect this process. **Eligibility:** To join, participants must weigh at least 50 kg (about 110 lbs), have a body mass index (BMI) between 18 and 30, and commit to using two forms of birth control from the start of the study until 90 days after the last drug dose. Participants must be willing to follow study rules and give written consent. **Exclusion Criteria:** Participants cannot join if they have infections like hepatitis B, hepatitis C, HIV, or COVID-19. They must not have abused alcohol or drugs, taken other research drugs within 28 days before the study, or used certain medications. Participants should not have any serious health issues. **Key Points:** - **Duration:** The study lasts from the first dose through 90 days post-study drug. - **Commitment:** Participants must follow study requirements and control birth. - **Eligibility:** Includes weight and BMI requirements, and excludes certain infections and drug use. **Consider all eligibility criteria and commitments before deciding to participate.**
Study details
    Healthy Volunteer Study

NCT06204679

Atea Pharmaceuticals, Inc.

24 January 2024

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