Image

A Study of CLE-100 (Oral Esketamine) as an Adjunctive Treatment to Standard Antidepressants for Major Depressive Disorder

Recruiting
18-65 years
Both
Phase 2
  • Simplified (AI rewritten)
  • Technical (Original)

This study is testing a new medicine, **CLE-100** (also called oral esketamine), for people with Major Depressive Disorder (MDD) who do not respond well to regular antidepressants. MDD is a condition where a person feels very sad or hopeless for a long time. The study wants to see if CLE-100 can help when taken with their usual medicine. Participants will take CLE-100 or a placebo (looks like the medicine but isn’t) once a day for 4 weeks. If they complete this part and qualify, they can continue taking CLE-100 for 6 more months.

  • The study lasts 4 weeks, with a chance for a 6-month extension.
  • Participants will take medicine once a day and keep using their current antidepressant.
  • Participation requires 2-5 visits to the study site.
Print
Study details
    Adjunctive Treatment of Major Depressive Disorder (MDD)

NCT06340958

Clexio Biosciences Ltd.

8 July 2024

Contact a study center
Not finding the right Trial?

You can also call our Patient navigators who can help you to find the right trial.

Call now
Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact

site

  Other languages supported:

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.