AHEAD 3-45 Study is a research study examining the effects of a drug called lecanemab in people with early signs of Alzheimer's disease. Alzheimer's is a disease that affects the brain and causes memory loss. The study will compare lecanemab with a placebo, which is a harmless pill that has no effect, to see if it can help with memory and reduce amyloid, a brain substance linked to Alzheimer's, using special brain scans called PET scans.
The study will last about 216 weeks (over 4 years), and participants must be between 55 to 80 years old. They need to have a family member or friend to help provide information. Safety and side effects will also be checked.
- Study Length: About 4 years with regular check-ups.
- Participant Requirements: Must have a study partner (family or friend) for support.
- Risks and Benefits: The study checks the drug's safety and potential to help memory and brain health.
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