**Study Overview:** This research is testing if spironolactone, a blood pressure medicine, is safe for older African American adults with memory problems, like those in early Alzheimer’s. Spironolactone works by blocking a hormone called aldosterone that can affect blood pressure and brain blood vessels. The study will see if it helps with memory and thinking.
**Participation Details:**
- Participants will take either spironolactone or a placebo (a pill with no medicine) for one year.
- There will be 4 to 5 visits during the study for tests and check-ups.
- Tests include memory and thinking questionnaires and an ultrasound to check blood vessel stiffness.
**Key Points:**
- **Length:** Participation lasts one year.
- **Visits:** Expect 4 to 5 study visits.
- **Compensation:** Not mentioned, but you'll help with important research.
Before joining, you must be an African American adult with mild cognitive impairment, among other criteria. People with certain health issues or who can't follow study procedures may not be eligible. If chosen, you will be closely monitored for any side effects. This study aims to find new ways to help with Alzheimer's, especially in African Americans.
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