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Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

Study on cholesterol-lowering effects in older adults.

Recruiting
75 years and older
All
Phase 4

PREVENTABLE is a study to see if a drug called atorvastatin can help older adults stay healthy. Atorvastatin is a type of medicine known as a statin, which helps lower cholesterol, a fatty substance in the blood that can cause heart problems. This study involves about 20,000 adults aged 75 or older from across the U.S. who do not have heart disease or dementia (a condition affecting memory and thinking). Participants will either take atorvastatin or a placebo (a fake pill) for up to 5 years. The goal is to see if atorvastatin can help reduce deaths, dementia, and disability. Participants will have regular phone check-ins and may need in-person visits if there are concerns about their health. The study is convenient because the study drug will be mailed to participants' homes every 90 days.

  • Length: Up to 5 years
  • Visits: Phone check-ins, possible in-person visits
  • Compensation: Not mentioned

Eligible participants must be 75 or older, live in the community, and speak English or Spanish. They must not have heart disease, dementia, or certain other health issues.

Study details
    Cognitive Impairment
    Mild
    Dementia
    Cardiovascular Diseases

NCT04262206

Duke University

27 June 2024

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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