Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

PREVENTABLE is a study to see if a medicine called atorvastatin (a type of statin, which helps lower cholesterol) can help prevent bad health outcomes like death or memory problems in older people. In this study, people 75 years or older who don’t have heart or memory problems will take either atorvastatin or a placebo (a pill that doesn't do anything) for about 3.8 years. The study wants to include 20,000 people from around the U.S. Participants will have check-ins by phone and sometimes in person.

People in the study will get a supply of the study pills every three months by mail. They will also have some tests to check their health, like blood tests and simple physical and memory checks. The study will help see if atorvastatin can keep older people healthy longer. If you are interested, you might need to visit a study site or talk on the phone to join. The study is looking for people who are 75 or older, living in the community, and can speak English or Spanish.

• The study lasts up to 5 years, with phone check-ins.
• Participants receive study medication by mail.
• Some visits may be required for health tests.