Alzheimer's Disease Neuroimaging Initiative 3 (ADNI3) is a study to help understand Alzheimer's Disease (AD) better. AD is a brain illness that affects memory and thinking. The study involves 1,070-2,000 participants aged 55-90, including those with normal cognition, mild cognitive impairment (MCI), and mild AD dementia. It will take place at 59 sites in the US and Canada. Participants will undergo tests like brain scans (PET and MRI), cognitive tests, and give samples for up to 5 years. The study aims to find better ways to diagnose and track AD using biomarkers—substances that indicate the presence of a disease.
Participants must not have other major brain diseases and must be willing to have procedures like lumbar punctures. People from previous ADNI studies can join again. The research focuses on improving future treatments for people with AD by studying how the disease progresses.
NCT02854033
University of Southern California
27 June 2024
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