Diffuse gliomas are a type of brain tumor that can be very serious, especially when they are grade 4. This study focuses on something called microRNAs, which are tiny pieces of genetic information that play a big role in how cells behave. Some microRNAs are linked to cancer, as they can help tumors grow and spread. Researchers want to see if the levels of these microRNAs in blood can help tell the difference between a tumor growing back and something called radionecrosis, which is tissue damage from radiation treatment.

Here's what you need to know:

• This study is for patients with grade 4 diffuse glioma who had surgery at Caen University Hospital.
• Participants will need to have regular brain scans and blood tests to check microRNA levels.
• It's important to know there are risks involved, like possible side effects from further treatments if the tumor comes back.