This study is an "open-label extension," meaning everyone knows what treatment is given. It's for people with *severe asthma* who were in earlier studies. **Asthma** is a condition that makes it hard to breathe. This study checks if the medicine, **GSK3511294 (Depemokimab)**, is safe and works well over time. There are specific rules to join: you must have finished earlier studies and be able to follow the study's rules. You can't join if your health has worsened, have certain health problems, or are pregnant. The study lasts for 12 months.

• **Duration:** 12 months
• **Eligibility:** Completed previous studies, no major health changes
• **Restrictions:** No current smokers or pregnant participants

Participants will help learn more about how this medication works long-term for asthma. It's important to think about if this study fits your life and health situation before joining. 😊