This study is testing a medicine called **dexpramipexole** to see if it helps people with severe eosinophilic asthma, a type of asthma where certain white blood cells (eosinophils) are too high. The study aims to check if the medicine is safe and works well. Participants must be at least 12 years old and have asthma that is hard to control even with regular treatments. To join, you need a doctor's note saying you've had asthma for at least a year and a certain level of eosinophils in your blood. You should also have been using asthma medications regularly for a while. The study will involve several visits to the doctor over time. **Key Points:** - **Visits:** Multiple doctor visits are required. - **Compensation:** There may be compensation for participation. - **Risks:** As with any study, there are risks, like potential side effects. Participants cannot join if they have recently had severe asthma attacks, have other lung diseases, or are pregnant. The study excludes those with certain medical conditions or those using specific medications. **Note:** Always discuss with your doctor before deciding to join a study.