The "Cancer Moonshot Biobank" is a research study collecting tissue and blood samples from cancer patients over time. This helps scientists understand how cancer changes with treatment. **Longitudinal study** means they collect samples from the same patients repeatedly. They look at how cancer reacts to drugs to improve future treatments.

Key Points to Consider:

• **Length of Study**: Samples and data are collected for at least 5 years.
• **Visits Needed**: Participants must provide tissue and blood samples at different times, including before, during, and after treatment.
• **Risks**: There is a risk with biopsy procedures, but they avoid high-risk procedures like brain biopsies.

Participants must have specific cancers like colorectal, lung, or breast cancer at advanced stages. They should be starting or already on standard cancer treatments. Some medical conditions may exclude participation, such as certain infections or prior experimental treatments. Participants aged 13 and older can join, and consent is required. This study aims to improve cancer research and treatments through these contributions.