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Open-label Study Comparing Iberdomide, Daratumumab and Dexamethasone (IberDd) Versus Daratumumab, Bortezomib, and Dexamethasone (DVd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)

Study comparing two treatments for relapsed multiple myeloma.

Recruiting
18 years and older
All
Phase 3

This study is for people with a type of blood cancer called multiple myeloma, which has come back or doesn't respond to treatment. It tests two treatments: one with iberdomide and one without it. Iberdomide, daratumumab, and dexamethasone (IberDd) are compared to daratumumab, bortezomib, and dexamethasone (DVd). The goal is to see which treatment works better and is safer. In the first part, 200 people will try different doses of iberdomide. In the second part, around 664 people will be split into two groups to try one of the treatments.

  • The study lasts until the disease gets worse or side effects are too strong.
  • Participants must have multiple myeloma and have tried 1-2 treatments before.
  • The study follows strict international research rules to protect participants.
Study details
    Multiple Myeloma

NCT04975997

Celgene

11 July 2024

Step 1

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Are you diagnosed with multiple myeloma?


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Learn more about clinical trials

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A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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