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Personalized Autologous Transplant for Multiple Myeloma

Recruiting
18 years and older
Both
Phase 1
  • Simplified (AI rewritten)
  • Technical (Original)

Multiple Myeloma Treatment Study: This study tests a chemo drug called melphalan, used for a type of blood cancer called multiple myeloma. Multiple myeloma affects plasma cells, which are part of the immune system. Patients receive a strong dose of melphalan, which is personalized based on how their body processes the drug. The main goal is to find the safest and most effective dose. After the drug is given, patients will undergo a process called an autologous stem cell transplant (ASCT), where their own healthy stem cells are returned to their body to help make new blood cells.

  • Study Duration: Patients are followed up for 90 days after treatment, with check-ins at 7, 14, 30, 60, and 90 days.
  • Eligibility: Patients must have multiple myeloma, meet certain health criteria, and agree to follow fertility guidelines.
  • Risks: The chemotherapy may have side effects, and pregnant or breastfeeding women cannot participate.

This study helps doctors learn more about the best way to use melphalan in treating multiple myeloma, aiming for safer and more effective cancer treatment. 🧬✨

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Study details
    Multiple Myeloma

NCT04483206

Emory University

11 July 2024

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