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A Study of an MMSET Inhibitor in Patients With Relapsed and Refractory Multiple Myeloma

Clinical trial: New MMSET inhibitor for relapsed multiple myeloma patients.

Recruiting
18 years and older
All
Phase 1
  • Simplified description (AI rewritten)
  • Technical description (Original)

**Relapsed and Refractory Multiple Myeloma (RRMM)** is a type of blood cancer that comes back or doesn't respond to treatment. This study is testing a new pill, called **KTX-1001**, to see if it's safe and works well for people with RRMM. The pill blocks a protein called MMSET, which helps cancer grow. The study has two parts. In Part A, researchers check for side effects and find the best dose. In Part B, they test this dose on patients with certain genetic changes to see how safe and effective it is.

  • Study Length: Cycle 1 lasts 28 days for dose finding.
  • Visits: Regular check-ups needed to monitor safety and effectiveness.
  • Eligibility: Must be 18+, have RRMM, and meet specific health criteria.

People can't join if they've had recent treatments, certain health conditions, or other active cancers. This study helps understand if KTX-1001 can be a new option for patients with this challenging condition.

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Study details
    Multiple Myeloma

NCT05651932

K36 Therapeutics, Inc.

11 July 2024

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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