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Low-Dose Radiotherapy in Treating Painful Bone Metastases in Patients With Multiple Myeloma

Exploring low-dose radiotherapy for bone pain in multiple myeloma patients.

Recruiting
18 years and older
All
Phase N/A

This study looks at how well low-dose radiotherapy helps with bone pain in people with multiple myeloma, a type of cancer that affects the blood and bone marrow. *Radiotherapy* uses high-energy rays to kill cancer cells and shrink tumors. This study is testing a low dose (2 Gy) given over two days to see if it helps with pain and has fewer side effects than standard treatments.

  • Participants will get radiation therapy over two days and have follow-up visits at 2, 4, and 8 weeks, and 6 months after treatment.
  • Patients should have multiple myeloma with painful bone spread, but cannot have had prior radiation or surgery on the painful area.
  • Study checks include pain relief, quality of life, and less pain medicine use.

Those in the study must be able to understand and agree to join by signing a consent form. It's important that they haven't had prior radiation on the painful bone and are not pregnant. This study may provide a more convenient, less disruptive, and potentially safer way to manage bone pain in multiple myeloma patients.

Study details
    Multiple Myeloma

NCT03858205

University of Southern California

11 July 2024

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