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Belantamab Mafodotin, Pomalidomide and Dexamethasone for the Treatment of High-Risk Myeloma

Trying new treatment for high-risk myeloma using three medications.

Recruiting
18 years and older
All
Phase 2

This study is testing a combination of three drugs—belantamab mafodotin, pomalidomide, and dexamethasone—on patients with high-risk myeloma, a type of blood cancer. Belantamab mafodotin is a special drug that targets cancer cells and delivers another drug called mafodotin to destroy them. Pomalidomide stops cancer cells from growing and spreading. Dexamethasone reduces inflammation and is often used with other cancer drugs.

Participants will receive these drugs in 28-day cycles, with some drugs given by IV (intravenous or directly into a vein) and others taken by mouth. This will continue unless there are side effects or the disease gets worse. After treatment, patients will have check-ups every three months.

  • Study involves regular cycles of treatment and follow-up visits.
  • Participants must meet specific health criteria to join.
  • Certain conditions and previous treatments may exclude participants.
Study details
    Plasma Cell Myeloma

NCT05208307

Emory University

11 July 2024

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What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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