This study is for kids aged 6-11 with *acute diarrhea*, which is a sudden increase in loose stools often caused by bacteria. The study is checking if a medicine called **rifaximin**, when given with *oral rehydration therapy (ORT)*, helps more than ORT alone. Rifaximin is an antibiotic that stays mostly in the gut, so it's less likely to affect other parts of the body. Participants will be divided into two groups: one will receive rifaximin and ORT, while the other will receive only ORT.

**Key Points:**

• Participants will take medicine for 3 days and attend up to 4 clinic visits over 5 days.
• Participants will need to provide blood and stool samples and keep a diary of symptoms.
• Participants will be monitored for any side effects and receive several follow-up calls.

Eligible participants must be healthy enough, without chronic diarrhea, and able to follow study directions. Girls must not be pregnant and must use effective birth control if necessary. This study helps understand if rifaximin can safely and effectively treat diarrhea in kids.