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Efficacy and Safety Prediction of Milrinone or Levosimendan as Initial Inotropic Drug Therapy in Patients With Acute and Advanced Heart Failure With Renal Insufficiency

Studying Milrinone vs. Levosimendan for heart failure with kidney issues.

Recruiting
18-80 years
All
Phase N/A
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study is for people with acute heart failure, a condition where the heart can't pump blood properly. It looks at two drugs, milrinone and levosimendan, to see which works better and safer for those whose kidneys may not be working well. The study develops a prediction model to help decide which drug might be better based on each patient's health and kidney function.

Inclusion: Adults aged 18-80 with heart failure, specifically with a heart function measure (LVEF) of less than 50%. Participants should agree to try levosimendan or milrinone.

Exclusion: Those with chronic heart failure (NYHA class I-II), severe kidney or liver issues, recent heart surgery, or certain heart problems. Also, people who recently used similar heart drugs or lack recent health tests can't join.

  • Study involves comparing two drugs for heart failure treatment.
  • Participants must meet specific health criteria.
  • Excludes those with certain health conditions or recent heart treatments.
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Study details
    Heart Failure
    Levosimendan
    Milrinone
    Efficacy
    Safety

NCT06205758

Yi Han

24 January 2024

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