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Found 407 clinical trials

Laterally Rotated Flap for Soft Tissue Augmentation Around Maxillary Loaded Osseointegrated Dental Implant

Peri-implant mucositis is one of the most common peri-implant diseases. It was reported in more than 20% of the subjects rehabilitated with dental implants (Lee et al. 2017; Rodrigo et al. 2018; Wada et al. 2019). Furthermore, a significant association was found between peri-implant mucositis, and smoking, implant maintenance and …

All
Phase N/A

Interindividual Variation in Response to Green Coffee

The study is a multifaceted approach to investigate the effects of regular consumption of green coffee rich in polyphenols (hydroxycinnamic acids) on weight, body composition, cardiometabolic and inflammatory biomarkers in a sample population of overweight and obese people aimed at identifying a population of responders to green coffee experimenting the …

20-65 years
All
Phase N/A

Intervention Program of a Job Crafting

The implementation of effective intervention programs is crucial in enhancing the overall well-being and performance of healthcare professionals, particularly in demanding environments such as nursing

20-60 years
All
Phase N/A

Open-Label Extension Study to Evaluate the Safety of Efgartigimod in Adult Patients With Primary Sjögren's Syndrome

Efgartigimod contributes to successfully treat pSS and has the potential to improve disease manifestations by the reduction of IgG autoantibodies in pSS. This open-label extension study will evaluate the long-term safety of efgartigimod in participants with pSS who have completed the treatment period of the qualifying efgartigimod studies (including ARGX-113-2106).

18 years and older
All
Phase 2

The Effectiveness of Cervical Kinesio Taping in Migraine

Migraine is a common episodic headache disorder accompanied by neurological, gastrointestinal and autonomic changes.Migraine symptoms have a wide range, neck pain is seen in most migraine attacks, and accompanying neck pain is considered one of the important factors that increase migraine-related disability. It has been shown that various physical therapy …

18-65 years
Female
Phase N/A

Physician Reasoning on Management Cases With Large Language Models

This study will evaluate the effect of providing access to GPT-4, a large language model, compared to traditional management decision support tools on performance on case-based management reasoning tasks.

All
Phase N/A

Different Menstrual Cycle in Eating Behavior Following Resistance Exercise

The study aims to provide insights into how menstrual cycle phases impact appetite responses to resistance exercise in young women. Healthy young women will participate in four trials: the exercise session in the follicular phase, the exercise session in the luteal phase, the control session in the follicular phase, and …

20-30 years
Female
Phase N/A

Clinical Study of GPA33-specific PET/CT for the Diagnosis of Colorectal Cancer

In this study, we will investigate the diagnostic efficacy and safety of [68Ga]Ga/[18F]F-H3RESCA-WWH347 in colorectal cancer, and evaluate the sensitivity and specificity of the use of [68Ga]Ga/[18F]F-H3RESCA-WWH347 in diagnosing colorectal cancer. This study will provide a new method for the noninvasive target-specific diagnosis of colorectal cancer, and provide an intuitive …

18-65 years
All
Phase N/A

Mild Water-filtered Infrared-A Whole-body Hyperthermia in Patients With Post-COVID Syndrome (HyPoCo)

This study examines the efficacy of mild water-filtered whole-body hyperthermia during outpatient treatment in patients with post-COVID syndrome. The aim is to evaluate whether there can be an improvement in fatigue and quality of life. The duration of the study extends over a treatment period of approximately 2 weeks with …

18-75 years
All
Phase N/A

A Study to Evealuate Safety and Immunogenicity of TI-0010 SARS-CoV-2 Vaccine in Healthy Adults

This study is a randomized, double-blind, placebo controlled clinical exploratory study to evaluate the safety, tolerability and immunogenicity of TI-0010 vaccine in healthy adults aged 18-59. TI-0010 was manufactured by Therorna Inc. TI-0010 is a novel lipid nanoparticles (LNP) -encapsulated circRNA-based vaccine targeting RBD of SARS-CoV-2. Up to one hundred …

18-59 years
All
Phase 1

Simplify language using AI